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Study: Cannabis Extracts Mitigate Muscle Stiffness In Multiple Sclerosis Patients


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Ola a todos, achei melhor postar esta notícia original, se puderem ajudar traduzindo, é delicado isso. Valew

July 24, 2012

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[Editor's note: This post is excerpted from this week's forthcoming NORML weekly media advisory.

To have NORML's news alerts and legislative advisories delivered straight to your in-box, sign up here.]

The oral administration of cannabis extracts significantly reduces muscle stiffness in patients with multiple sclerosis (MS), according to just published clinical trial data published in theJournal of Neurology, Neurosurgery & Psychiatry.Investigators at the University of Plymouth, Clinical Neurology Research Group, in the United Kingdom assessed the use of cannabinoids versus placebo in 279 subjects with MS over a twelve-week period. Cannabis extracts in the study contained standardized doses of THC and cannabidiol (CBD), a non-psychoactive constituent in cannabis, contained in a soft, gelatin capsule.

Investigators reported that oral cannabis extracts were “superior” over placebo in the treatment of MS-associated muscle stiffness and pain.Authors concluded: “Treatment with standardized oral extract of cannabis sativa relieved muscle stiffness. The proportion of participants experiencing relief was almost twice as large in the cannabis extract group as in the placebo group. … Effective pain relief is also achieved by cannabis extracts, especially in patients with a high baseline pain score. Our findings suggest that standardized cannabis extracts can be clinically useful in treating the highly complex phenomenon of spasticity in MS.”

In May, clinical trial data published in the Journal of the Canadian Medical Association reported that cannabis inhalation significantly mitigates spasticity and pain in patients with treatment-resistant multiple sclerosis.Separate clinical trials assessing the administration of oral cannabis extracts on patients with MS haveindicated that cannabinoids can alleviate symptoms of the disease long-term and may also act in ways to mitigate MS progression. Sativex, an oral spray containing plant cannabis extracts, is presently legal by prescription to treat MS-related symptoms in over a dozen countries, including Canada, Germany, Great Britain, New Zealand, and Spain. Nonetheless, the National MS Society of the United States shares little enthusiasm for cannabis as a potential treatment for multiple sclerosis, stating, “Studies completed thus far have not provided convincing evidence that marijuana or its derivatives provide substantiated benefits for symptoms of MS.”Full text of the study, “Multiple Sclerosis and Extract of Cannabis: results of the MUSEC trial,” appears in the Journal of Neurology, Neurosurgery & Psychiatry.

Fonte: http://blog.norml.or...rosis-patients/

Notícia vinculada: http://cannabismedicinal.org

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  • Usuário Growroom

Deve ter alguns erros não tive tempo de revisar.....

A administração do extrato de cannabis reduz significantemente o erigecimento muscular em pacientes com esclerose múltipla (MS), de acordo com o teste clínico públicado no jornal de Neurologia e neurocirurgia e psiquiatria.

Investigadores da Universidade de Plymouth, do grupo de pesquisa de neurologia,realizada na grã-bretanha a pesquisa continha 279 pacientes de esclerose,o experiemento consistia em testar os cannabinoides versus placebo durante um período de cerca de doze semanas.

O extrato de cannabis contém doses padronizadas de THC e Cannabidiol (CBD), o contra parte não psicoativo da cannabis, armazenado em uma macia capsula gelatinosa.

os pesquisadores relataram que o extrato oral de cannabis eram muito superiores ao placebo no tratamento ao erigecimento associado a esclerose múltipla sinônimo de dor e sofrimento.

Autores concluíram "O tratamento com o extrato de cannabis sativa aliviam o enrigecimento muscular.Na proporção os pacientes utilizando o extrato experimentavam uma melhora de quase duas vezes sobre o outro grupo com o placebo.Um alivio efetivo da dor é obtido com o extrato de cannabis especialmente em pacientes com o nível de dor alto.Nossos estudos indicam que o extrato é clinicalmente aplicável para o altamente complexo fenômeno dos espasmos na esclerose."

Em maio, o testes clinicos públicados no Jornal da associação Médica canadense relataram que inalação de cannabis significantemente atenuam os espamos e a dor relacionados a esclerose em pacientes com resistência ao tratamento.

Testes clinicos separados avaliaram que a administração oral do extrato de cannabis em pacientes com esclerose,indicaram que os cannabinoids aliviam os sintomas da doença a longo prazo e podem também suavizar a progressão.Sativex o spray oral contendo o extrato de cannabis, é atualmente legal por prescrição para tratamento da esclerose múltipla em uma dúzia de países incluindo Alemanha,Canada,Grã-Bretanha,Nova Zelândia e Espanha.

Alheio as pesquisas,a Sociedade Nacional de Esclerose Múltipla dos Estados Unidos não demonstra nenhum entusiasmo sobre a cannabis se tornar um potencial tratamento para esclerose múltipla.Declarando que: "Os estudos apresentados até agora não comprovam que a Maconha ou nenhum de seus derivados podem proporcionar beneficios substantivos para o sintomas da Esclerose Múltipla."

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