Cannabis Does Not Cause Psychosis By Itself.

[Canadense]

http://www.ncbi.nlm.nih.gov/pubmed/24309013

Cannabis does not cause psychosis by itself. In genetically vulnerable individuals, while cannabis may modify the illness onset, severity and outcome, there is no evidence from this study that it can cause the psychosis

Schizophr Res. 2013 Dec 2. pii: S0920-9964(13)00610-5. doi: 10.1016/j.schres.2013.11.014. [Epub ahead of print]

A controlled family study of cannabis users with and without psychosis.

Proal AC, Fleming J, Galvez-Buccollini JA, Delisi LE.

Source

Harvard Medical School, 25 Shattuck St, Boston, MA 02115, United States.

Abstract

BACKGROUND:

Cannabis is one of the most highly abused illicit drugs in the world. Several studies suggest a link between adolescent cannabis use and schizophrenia. An understanding of this link would have significant implications for legalization of cannabis and its medicinal value. The present study aims to determine whether familial morbid risk for schizophrenia is the crucial factor that underlies the association of adolescent cannabis use with the development of schizophrenia.

METHODS:

Consecutively obtained probands were recruited into four samples: sample 1: 87 non-psychotic controls with no drug use; sample 2: 84 non-psychotic controls with cannabis use; sample 3: 32 patients with a schizophrenia spectrum psychosis with no drug use; sample 4: 76 patients with schizophrenia spectrum psychosis with cannabis use. All cannabis using subjects used this drug during adolescence, and no other substance, with the exception of alcohol. Structured interviews of probands and family informants were used to obtain diagnostic information about probands and all their known relatives.

RESULTS:

There was an increased morbid risk for schizophrenia in relatives of the cannabis using and non-using patient samples compared with their respective non-psychotic control samples (p=.002, p<.001 respectively). There was no significant difference in morbid risk for schizophrenia between relatives of the patients who use or do not use cannabis (p=.43).

CONCLUSIONS:

The results of the current study suggest that having an increased familial morbid risk for schizophrenia may be the underlying basis for schizophrenia in cannabis users and not cannabis use by itself.

Published by Elsevier B.V.

[lolverdinlol]

esfrega esfrega na cara dele, esfrega esfrega na cara dela!!!

Chupa!

[flokinhos]

Um conhecido foi `diagnosticado` com esquizofrenia esses dias, ele tem 25 anos e usa cannabis e alcool a uns 10 anos.

Não tive contato com a família, mas pelo que pude perceber até de um broder em comum que fuma maconha também é que a culpada é a mardida da erva, esquecendo o uso continuo de alcool por anos, mesmo sendo menor de idade e alguns usos exporádicos de cocaina e crack na fase adulta.

Não sou médico, mas acho que não deveriam culpa a erva.