fuck_off

Quem me garante que vc nao eh puliça?

Agora fiquei com uma duvida : praticamente todas as compras de seeds sao feitas em sites estrangeiros, é seguro pagar no cc? A PF pode pedir pro banco aqui no BR o meu extrato, e ver laH a operacao com o site extrangeiro? Paypal eh mais seguro ? Novamente obrigado CJGR

A primavera da america latina ta demorando pra chegar.....

Ahhh, agora sim

Oq isso tem a ver com maconha?

Ai que saudade dessa época

Medico alcoolatra nao da nada pode chapar o dia todo q ninguem reclama.... Nao sai no g1 se o medico beber 3 litros de cachaça por dia. Qta hipocrisia, vtnc

Sensacional a materia vamos comentar la no site da folha!

50g de prensado ou do green? Pena msm q vao acabar as palas...

Aguaugaguguaugagugauhauahu adoro qdo as fotos tomam esse rumo

Qual clinica? Do laranjada?

Exatamente.....mais acho q com esses varios trabalhos internacionais publicados em revistas respeitaveis agente ja pode "provar" que ela tem seus efeitos no sentido de abaixar a PIO. Tambem acredito que os colirios tradicionais dificilmente vao sair de cena, na melhor das hipoteses a cannabis podera ser associada ao seu uso.

Bela compilacao, cannaSP! Acho q nosso trabalho deveria abordar principalmente as claras evidencias que a cannabis funciona no tratamento dessa doenca, seus baixissimos niveis de efeitos colaterais quando comparados com as dificuldades encontradas no tratamento atual. E em seguida discorrermos sobre o compromisso que os médicos assumem de sempre indicar o melhor tratamento para seus pacientes, sempre expondo os pros e contras de cada um deles, e tomar a decisao em conjunto com o doente. Mostrar que a situacao atual nao permite que isso aconteça, graças à lista da ONU que foi feita baseada em equivocos notáveis, e que manteve os olhos da ciencia totalmente fechados com relacao as propriedades da cannabis, principalmente em nosso país. Infelizmente esse final de ano esta um pouco corrido, nao estou tendo muito tempo para ajudar, a partir da proxima semana isso deve melhorar. Abc

All about the fucking money

Endocannabinoids in the retina: from marijuana to neuroprotection. Yazulla S. Source Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY 11794-5230, United States. stephen.yazulla@stonybrook.edu Abstract The active component of the marijuana plant Cannabis sativa, Delta9-tetrahydrocannabinol (THC), produces numerous beneficial effects, including analgesia, appetite stimulation and nausea reduction, in addition to its psychotropic effects. THC mimics the action of endogenous fatty acid derivatives, referred to as endocannabinoids. The effects of THC and the endocannabinoids are mediated largely by metabotropic receptors that are distributed throughout the nervous and peripheral organ systems. There is great interest in endocannabinoids for their role in neuroplasticity as well as for therapeutic use in numerous conditions, including pain, stroke, cancer, obesity, osteoporosis, fertility, neurodegenerative diseases, multiple sclerosis, glaucoma and inflammatory diseases, among others. However, there has been relatively far less research on this topic in the eye and retina compared with the brain and other organ systems. The purpose of this review is to introduce the "cannabinergic" field to the retinal community. All of the fundamental works on cannabinoids have been performed in non-retinal preparations, necessitating extensive dependence on this literature for background. Happily, the retinal cannabinoid system has much in common with other regions of the central nervous system. For example, there is general agreement that cannabinoids suppress dopamine release and presynaptically reduce transmitter release from cones and bipolar cells. How these effects relate to light and dark adaptations, receptive field formation, temporal properties of ganglion cells or visual perception are unknown. The presence of multiple endocannabinoids, degradative enzymes with their bioactive metabolites, and receptors provides a broad spectrum of opportunities for basic research and to identify targets for therapeutic application to retinal diseases.

Abstract PURPOSE: The purpose of this study was to assess the effect on intraocular pressure (IOP) and the safety and tolerability of oromucosal administration of a low dose of delta-9-tetrahydrocannabinol (Delta-9-THC) and cannabidiol (CBD). PATIENTS AND METHODS: A randomized, double-masked, placebo-controlled, 4 way crossover study was conducted at a single center, using cannabis-based medicinal extract of Delta-9-THC and CBD. Six patients with ocular hypertension or early primary open angle glaucoma received a single sublingual dose at 8 AM of 5 mg Delta-9-THC, 20 mg CBD, 40 mg CBD, or placebo. Main outcome measure was IOP. Secondary outcomes included visual acuity, vital signs, and psychotropic effects. RESULTS: Two hours after sublingual administration of 5 mg Delta-9-THC, the IOP was significantly lower than after placebo (23.5 mm Hg vs. 27.3 mm Hg, P=0.026). The IOP returned to baseline level after the 4-hour IOP measurement. CBD administration did not reduce the IOP at any time. However, the higher dose of CBD (40 mg) produced a transient elevation of IOP at 4 hours after administration, from 23.2 to 25.9 mm Hg (P=0.028). Vital signs and visual acuity were not significantly changed. One patient experienced a transient and mild paniclike reaction after Delta-9-THC administration. CONCLUSIONS: A single 5 mg sublingual dose of Delta-9-THC reduced the IOP temporarily and was well tolerated by most patients. Sublingual administration of 20 mg CBD did not reduce IOP, whereas 40 mg CBD produced a transient increase IOP rise. http://www.ncbi.nlm.nih.gov/pubmed/16988594 Effect of sublingual application of cannabinoids on intraocular pressure: a pilot study Um dos problemas desse estudo, imo, eh que testaram os canabinoides separadamente, alem do n baixo. Muita gente acredita que eh a combinacao dos mais de sessenta cannabinoides da planta que eh responsavel pelos maiores beneficios....

Perfeito, acho q ja temos todas as infos necessarias. Realmente a via de adm oral parece a mais atraente, o uso cronico de coliros causa problemas na superficie ocular devido principalmente aos conservantes da sua composicao.... Alem do fato do efeito ser mais prolongado... Vou procurar mais artigos aqui e vou postando se achar alguma informacao nova.

Marisa Lobo, é voce?

Incrivel ateh onde isso vai..... Qto mais se cava mais merda se acha..... It's all about money, always....

Quem for dar o play nesse video ai eh bom deixar o remedio do lado e se preparar pq essa sra Marisa Loba causa náuseas.